Correlation of the Commercial Anti-SARS-CoV-2 Receptor Binding Domain Antibody Test with the Chemiluminescent Reduction Neutralizing Test and Possible Detection of Antibodies to Emerging Variants-Reference-Cited by-同舟云学术

Correlation of the Commercial Anti-SARS-CoV-2 Receptor Binding Domain Antibody Test with the Chemiluminescent Reduction Neutralizing Test and Possible Detection of Antibodies to Emerging Variants

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Morinaga Yoshitomo¹^ORCID,Tani Hideki¹²^ORCID,Terasaki Yasushi³,Nomura Satoshi³,Kawasuji Hitoshi⁴,Shimada Takahisa¹²,Igarashi Emiko²,Saga Yumiko¹²,Yoshida Yoshihiro¹,Yasukochi Rei⁴,Kaneda Makito⁴,Murai Yushi⁴,Ueno Akitoshi⁴,Miyajima Yuki⁴,Fukui Yasutaka⁴,Nagaoka Kentaro⁴,Ono Chikako⁵⁶,Matsuura Yoshiharu⁵⁶,Fujimura Takashi³,Ishida Yoichi³,Oishi Kazunori⁷,Yamamoto Yoshihiro⁴

Affiliation:

1. Department of Microbiology, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan

2. Department of Virology, Toyama Institute of Health, Toyama, Japan

3. Toyama City Hospital, Toyama, Japan

4. Department of Clinical Infectious Diseases, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan

5. Laboratory of Virus Control, Center for Infectious Disease Education and Research (CiDER), Osaka University, Osaka, Japan

6. Laboratory of Virus Control, Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan

7. Toyama Institute of Health, Toyama, Japan

Abstract

This study provides a diagnostic evidence of test validity, which can lead to vaccine efficacy and proof of recovery after COVID-19. It is not easy to know neutralization against SARS-CoV-2 in the clinical laboratory because of technical and biohazard issues.

Funder

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00560-21

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