Differential Antibody Response to mRNA COVID-19 Vaccines in Healthy Subjects

Author:

Wheeler Sarah E.1ORCID,Shurin Galina V.1,Yost Mary1,Anderson Adam2,Pinto Lisa2,Wells Alan1,Shurin Michael R.13ORCID

Affiliation:

1. Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

2. Bio-Rad Laboratories, Inc., Benicia, California, USA

3. Department of Immunology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

Abstract

Now that authorized vaccines for COVID-19 have been widely used, it is important to understand how they induce antivirus antibodies, which antigens are targeted, how long antibodies circulate, and how personal health conditions and age may affect this humoral immunity. Here, we report induction and time course of multiple anti-SARS-CoV-2 antibody responses in healthy individuals immunized with Pfizer and Moderna mRNA vaccines.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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