Pre-Vaccine Positivity of SARS-CoV-2 Antibodies in Alberta, Canada during the First Two Waves of the COVID-19 Pandemic-Reference-Cited by-同舟云学术

Pre-Vaccine Positivity of SARS-CoV-2 Antibodies in Alberta, Canada during the First Two Waves of the COVID-19 Pandemic

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Charlton Carmen L.¹²³,Nguyen Leonard T.⁴,Bailey Ashley¹,Fenton Jayne¹,Plitt Sabrina S.⁵,Marohn Carol⁴,Lau Cheryl⁴,Hinshaw Deena⁶⁷⁸,Lutsiak Christie⁷,Simmonds Kimberley⁶⁷,Kanji Jamil N.¹²⁹^ORCID,Zelyas Nathan¹²,Lee Nelson¹⁰,Mengel Michael²⁴,Tipples Graham¹³¹¹

Affiliation:

1. Public Health Laboratory, Alberta Precision Laboratories, Alberta, Canada

2. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

3. Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada

4. Alberta Precision Laboratories, Edmonton, Alberta, Canada

5. Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada (PHAC), Ottawa, Ontario, Canada

6. Alberta Ministry of Health, Edmonton, Alberta, Canada

7. Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada

8. Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

9. Division of Infectious Diseases, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

10. Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

11. Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

Abstract

Using SARS-CoV-2 serology testing, we assessed the proportion of people in Alberta, Canada (population 4.4 million) positive for COVID-19 antibodies, indicating previous infection, during the first two waves of the COVID-19 pandemic (prior to vaccination programs). Linking these results with sociodemographic population data provides valuable information as to which groups of the population are more likely to have been infected with the SARS-CoV-2 virus to help facilitate public health decision-making and interventions.

Funder

Government of Alberta

Canadian Immunity Task Force

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00291-21

Reference32 articles.

1. Diagnosis and Management of First Case of COVID-19 in Canada: Lessons Applied From SARS-CoV-1

2. Retrospective testing of respiratory specimens for COVID-19 to assess for earlier SARS-CoV-2 infections in Alberta, Canada