Author:
van de Kassteele Jan,van Santen-Verheuvel Marga G.,Koedijk Femke D. H.,van Dam Alje P.,van der Sande Marianne A. B.,de Neeling Albert J.
Abstract
ABSTRACTSeventeen laboratories participated in a cooperative study to validate the regional susceptibility testing ofNeisseria gonorrhoeaein The Netherlands. International reference strains were distributed. Each laboratory determined the MICs of ciprofloxacin, penicillin, and tetracycline, for each strain by Etest. To explore a more transparent assessment of quality and comparability, a statistical regression model was fitted to the data that accounted for the censoring of the MICs. The mean MICs found by all of the laboratories except three were closer than one 2-fold dilution step to the overall mean, and the mean MICs of each antimicrobial agent were close to the MICs for the international reference strains. This approach provided an efficient tool to analyze the performance of the Dutch decentralized gonococcal resistance monitoring system and confirmed good and comparable standards.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献