Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches

Author:

Cakir Merve1234,Obernier Kirsten1234,Forget Antoine1234,Krogan Nevan J.1234

Affiliation:

1. Quantitative Biosciences Institute (QBI), University of California, San Francisco, California, USA

2. Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, California, USA

3. Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA

4. Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, California, USA

Abstract

Current epidemics, such as HIV or influenza, and the emergence of new threatening pathogens, such as the one causing the current coronavirus disease 2019 (COVID-19) pandemic, represent major global health challenges. While vaccination is an important part of the arsenal to counter the spread of viral diseases, it presents limitations and needs to be complemented by efficient therapeutic solutions.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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