Comprehensive Strain-Level Analysis of the Gut Microbe Faecalibacterium prausnitzii in Patients with Liver Cirrhosis

Author:

Chen Yaowen1,Liu Pu1,Liu Runyan1,Hu Shuofeng1,He Zhen1,Dong Guohua1,Feng Chao1,An Sijing1,Ying Xiaomin1

Affiliation:

1. Center for Computational Biology, Beijing Institute of Basic Medical Sciences, Beijing, China

Abstract

Most metagenomic studies focus on microbes at the species level, thus ignoring the different effects of different strains of the same species on the host. In this study, we explored the different microbes at the strain level in the intestines of patients with liver cirrhosis and of healthy people.

Funder

National Science and Technology Major Project

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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