Towards Translational Epidemiology: Next-Generation Sequencing and Phylogeography as Epidemiological Mainstays

Author:

Hepp Crystal M.12

Affiliation:

1. School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, Arizona, USA

2. The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA

Abstract

Next-generation sequencing, coupled with the development of user-friendly software, has achieved a level of accessibility that is revolutionizing the way we approach epidemiological investigations. We can sequence pathogen genomes and conduct phylogenetic analyses to assess transmission, identify from which country or city a pathogen originated, or which contaminated potluck item resulted in widespread foodborne illness.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Reference15 articles.

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4. Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10

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