Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae

Author:

Bulman Zackery P.1ORCID,Krapp Fiorella2ORCID,Pincus Nathan B.3ORCID,Wenzler Eric1ORCID,Murphy Katherine R.3,Qi Chao4,Ozer Egon A.2,Hauser Alan R.23ORCID

Affiliation:

1. Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, Illinois, USA

2. Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

3. Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

4. Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Abstract

Klebsiella pneumoniae can cause severe infections in the blood, urinary tract, and lungs. Resistance to carbapenems in K. pneumoniae is an urgent public health threat, since it can make these isolates difficult to treat.

Funder

Chicago Biomedical Consortium

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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