Successful Profiling of Plasmodium falciparum var Gene Expression in Clinical Samples via a Custom Capture Array-Reference-Cited by-同舟云学术

Successful Profiling of Plasmodium falciparum var Gene Expression in Clinical Samples via a Custom Capture Array

Published:2021-12-21 Issue:6 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Stucke Emily M.¹,Dara Antoine¹,Dwivedi Ankit²,Hodges Theresa K.²,Ott Sandra²,Coulibaly Drissa³,Koné Abdoulaye K.³,Traoré Karim³,Guindo Bouréima³,Tangara Bourama M.³,Niangaly Amadou³,Daou Modibo³,Diarra Issa³,Tolo Youssouf³,Sissoko Mody³,Tallon Luke J.²,Sadzewicz Lisa²,Zhou Albert E.¹,Laurens Matthew B.¹^ORCID,Ouattara Amed¹,Kouriba Bourema³,Doumbo Ogobara K.³,Takala-Harrison Shannon¹,Serre David²,Plowe Christopher V.¹,Thera Mahamadou A.³,Travassos Mark A.¹^ORCID,Silva Joana C.²⁴^ORCID

Affiliation:

1. Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

2. Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA

3. Malaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali

4. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

Abstract

Malaria parasites display antigens on the surface of infected red blood cells in the human host that facilitate attachment to blood vessels, contributing to the severity of infection. These antigens are highly variable, allowing the parasite to evade the immune system.

Funder

Meyerhoff Graduate Fellows Program

Burroughs Wellcome Fund

HHS | NIH | National Heart, Lung, and Blood Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

Howard Hughes Medical Institute

University of Maryland

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00226-21

Reference30 articles.

1. World Trade Report 2020

2. A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

3. Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity

4. Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates

5. Evolutionary analysis of the most polymorphic gene family in falciparum malaria

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