TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus-Reference-Cited by-同舟云学术

TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus

Published:2021-10-13 Issue:21 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sato Ko¹²³^ORCID,Hayashi Hideki⁴,Shimotai Yoshitaka⁵,Yamaya Mutsuo⁶,Hongo Seiji⁵,Kawakami Kazuyoshi²³,Matsuzaki Yoko⁵,Nishimura Hidekazu¹

Affiliation:

1. Virus Research Center, Clinical Research Division, Sendai Medical Center, Sendai, Miyagi, Japan

2. Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

3. Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

4. Medical University Research Administrator, Nagasaki University School of Medicine, Sakamoto, Nagasaki, Japan

5. Department of Infectious Diseases, Yamagata University Faculty of Medicine, Iida-Nishi, Yamagata, Japan

6. Department of Advanced Preventive Medicine for Infectious Disease, Tohoku University Graduate school of Medicine, Sendai, Miyagi, Japan

Abstract

Influenza C virus (ICV) is a pathogen that causes acute respiratory illness, mostly in children, but there are no anti-ICV drugs. ICV has only one kind of spike protein, the hemagglutinin-esterase (HE) glycoprotein on the virion surface, which possesses receptor-binding, receptor-destroying, and membrane fusion activities.

Funder

Clinical Research Division, Sendai Medical Center

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01296-21

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1. Studies on Survival of Influenza Virus Between Epidemics and Antigenic Variants of the Virus

2. Clinical Features of Influenza C Virus Infection in Children