Endocarditis with Ruptured Cerebral Aneurysm Caused by Cardiobacterium valvarum sp. nov

Author:

Han Xiang Y.1,Meltzer Michelle C.1,Woods Joan T.1,Fainstein Victor2

Affiliation:

1. Section of Clinical Microbiology, The University of Texas M. D. Anderson Cancer Center

2. Section of Infectious Diseases, The Methodist Hospital, Houston, Texas 77030

Abstract

ABSTRACT A fastidious gram-negative bacterium was isolated from the blood of a 37-year-old man who had insidious endocarditis with a sudden rupture of a cerebral aneurysm. Characterization of the organism through phylogenetic and phenotypic analyses revealed a novel species of Cardiobacterium , for which the name Cardiobacterium valvarum sp. nov. is proposed. C. valvarum will supplement the current sole species Cardiobacterium hominis , a known cause of endocarditis. Surgeries and antibiotic treatment cured the patient's infection and associated complications. During cardiac surgery, a congenital bicuspid aortic valve was found to be the predisposing factor for his endocarditis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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