SNX17 Facilitates Infection with Diverse Papillomavirus Types-Reference-Cited by-同舟云学术

SNX17 Facilitates Infection with Diverse Papillomavirus Types

Published:2013-01-15 Issue:2 Volume:87 Page:1270-1273
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Bergant Martina¹²,Banks Lawrence¹

Affiliation:

1. International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

2. Laboratory for Environmental Research, University of Nova Gorica, Nova Gorica, Slovenia

Abstract

ABSTRACT Previous studies have shown that the human papillomavirus type 16 (HPV-16) L2 capsid protein plays an essential role in viral infection, in part through its interaction with sorting nexin 17 (SNX17). We now show that this interaction between L2 and SNX17 is conserved across multiple PV types. Furthermore, we demonstrate that SNX17 is essential for infection with all PV types analyzed, indicating an evolutionarily highly conserved virus entry mechanism.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01991-12

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