Sakacin G, a New Type of Antilisterial Bacteriocin

Author:

Simon L.1,Fremaux C.2,Cenatiempo Y.1,Berjeaud J. M.1

Affiliation:

1. Laboratoire de Microbiologie Fondamentale et Appliquée, EA 2224, IBMIG, 86022 Poitiers

2. Rhodia Food, 86220 Dangé Saint-Romain, France

Abstract

ABSTRACT Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2 . Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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