Isolation and Identification of Aspergillus fumigatus Mycotoxins on Growth Medium and Some Building Materials

Author:

Nieminen Susanna M.1,Kärki Riikka2,Auriola Seppo1,Toivola Mika3,Laatsch Hartmut4,Laatikainen Reino5,Hyvärinen Anne3,von Wright Atte2

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Institute of Applied Biotechnology

3. Division of Environmental Health, National Public Health Institute, 70701 Kuopio, Finland

4. Department of Organic Chemistry, University of Goettingen, Goettingen D-37077, Germany

5. Department of Chemistry, University of Kuopio, 70211 Kuopio

Abstract

ABSTRACT Genotoxic and cytotoxic compounds were isolated and purified from the culture medium of an indoor air mold, Aspergillus fumigatus . One of these compounds was identified as gliotoxin, a known fungal secondary metabolite. Growth of A. fumigatus and gliotoxin production on some building materials were also studied. Strong growth of the mold and the presence of gliotoxin were detected on spruce wood, gypsum board, and chipboard under saturation conditions.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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