The Washing Machine as a Reservoir for Transmission of Extended-Spectrum-Beta-Lactamase (CTX-M-15)-Producing Klebsiella oxytoca ST201 to Newborns-Reference-Cited by-同舟云学术

The Washing Machine as a Reservoir for Transmission of Extended-Spectrum-Beta-Lactamase (CTX-M-15)-Producing Klebsiella oxytoca ST201 to Newborns

Published:2019-11-15 Issue:22 Volume:85 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Schmithausen Ricarda M.¹^ORCID,Sib Esther¹,Exner Martin¹,Hack Sylvia¹,Rösing Claudia¹,Ciorba Patrick¹,Bierbaum Gabriele²,Savin Mykhailo³,Bloomfield Sally F.⁴,Kaase Martin⁵,Jacobshagen Anja¹,Gemein Stefanie¹,Gebel Jürgen¹,Engelhart Steffen¹,Exner Daniel⁶

Affiliation:

1. Institute for Hygiene and Public Health, University Hospital Bonn, Bonn, Germany

2. Institute of Medical Microbiology, Immunology, and Parasitology, Bonn, Germany

3. Department of Preventive Health Management, Institute of Animal Science, Bonn, Germany

4. London School of Hygiene and Tropical Medicine, University of London, London, United Kingdom

5. National Reference Laboratory for Multidrug-Resistant Gram-Negative Bacteria, Department of Medical Microbiology, Ruhr University Bochum, Bochum, Germany

6. Department of General, Visceral, Thoracic, and Vascular Surgery, University Hospital Bonn, Bonn, Germany

Abstract

Washing machines should be further investigated as possible sites for horizontal gene transfer (ESBL genes) and cross-contamination with clinically important Gram-negative strains. Particularly in the health care sector, the knowledge of possible (re-)contamination of laundry (patients’ clothes and staff uniforms) with multidrug-resistant Gram-negative bacteria could help to prevent and to control nosocomial infections. This report describes an outbreak with a single strain of a multidrug-resistant bacterium ( Klebsiella oxytoca sequence type 201) in a neonatal intensive care unit that was terminated only when the washing machine was removed. In addition, the study implies that changes in washing machine design and processing are required to prevent accumulation of residual water where microbial growth can occur and contaminate clothes.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01435-19

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