Mechanism of action of aflatoxin B1 in Bacillus megaterium

Author:

Tiwari R P,Dham C K,Bhalla T C,Saini S S,Vadehra D V

Abstract

Bacillus megaterium cells from various growth phases were equally susceptible to the lethal effects of aflatoxin B1. Known surfactants (EDTA and Tween-80) accentuated the effects of aflatoxin B1. Viability and inulin uptake in aflatoxin B1-exposed cells decreased considerably. The effect was concentration dependent. A straight-line relationship observed in the death curve indicated a single target for aflatoxin B1 action in B. megaterium. Leakage of intracellular constituents in B. megaterium was also concentration dependent, and this can be related to the extent of cell membrane damage.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference28 articles.

1. Effect of aflatoxin B1 on induction of histidase;Anand S. R.;Indian J. Exp. Biol.,1971

2. Antimicrobial activity of aflatoxins;Arai T.;J. Bacteriol.,1967

3. Biochemical alterations in B. megaterium was produced by aflatoxin B;Beuchat L. R.;Appl. Microbiol.,1971

4. Gibberelic acid induced lipase and alpha amylase formation and their inhibition by aflatoxins;Black H. S.;Biochem. Biophys. Res. Commun.,1965

5. Biological detection of aflatoxin and patualin mycotoxin using B. thuringiensis;Boutibonnes P.;Bull. Acad. Vet. France.,1976

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3