Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi-Reference-Cited by-同舟云学术

Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi

Published:2018-09 Issue:9 Volume:86 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Lin Ying-Han¹,Chen Yue¹,Smith Trever C.¹,Karna S. L. Rajasekhar¹,Seshu J.¹

Affiliation:

1. South Texas Center for Emerging Infectious Diseases, Center of Excellence in Infection Genomics and Department of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA

Abstract

Borrelia burgdorferi responds to a variety of host-derived factors and appropriately alters its gene expression for adaptation under different host-specific conditions. We previously showed that various levels of acetate, a short-chain fatty acid (SCFA), altered the protein profile of B. burgdorferi .

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

DOD | United States Army | RDECOM | Army Research Office

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00217-18

Reference57 articles.

1. Insights into the Biology of Borrelia burgdorferi Gained Through the Application of Molecular Genetics

2. Gene Regulation in Borrelia burgdorferi