Molecular Epidemiology of Enterobacteriaceae Isolates Producing Extended-Spectrum β-Lactamases in a French Hospital

Author:

Lavigne Jean-Philippe12,Bouziges Nicole2,Chanal Catherine3,Mahamat Aba4,Michaux-Charachon Sylvie12,Sotto Albert15

Affiliation:

1. Laboratoire Universitaire d'Antibiologie, Faculté de Médecine, 30900 Nîmes

2. Laboratoire de Bactériologie, Virologie, et Parasitologie

3. Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont Ferrand Cedex, France

4. Département d'Information Médicale

5. Service de Médecine Interne B, CHU de Nîmes, Groupe Hospitalo-Universitaire de Carémeau, 30029 Nîmes Cedex 9

Abstract

ABSTRACT In 2002, 80 isolates of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) were collected from infected patients in our hospital. Enterobacter aerogenes was the most common bacterium isolated from all specimens (36.5%). The ESBLs were predominantly (90%) TEM derivatives (TEM-24, TEM-3). Pulsed-field gel electrophoresis highlighted that E. aerogenes , Klebsiella pneumoniae , and Citrobacter koseri had a clonal propagation.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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