Potential of a Simplified p24 Assay for Early Diagnosis of Infant Human Immunodeficiency Virus Type 1 Infection in Haiti-Reference-Cited by-同舟云学术

Potential of a Simplified p24 Assay for Early Diagnosis of Infant Human Immunodeficiency Virus Type 1 Infection in Haiti

Published:2007-10 Issue:10 Volume:45 Page:3416-3418
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

George Erik¹,Beauharnais Carole Anne²,Brignoli Emilio²,Noel Francine²,Bois Gyrlande²,De Matteis Rouzier Patricia²,Altenor Martine²,Lauture Daniel²,Hosty Marlène³,Mehta Sapna⁴,Wright Peter F.⁴,Pape Jean W.²

Affiliation:

1. Department of Medicine, Division of International Medicine and Infectious Diseases, Weill Medical College of Cornell University, New York, New York

2. Groupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO), Port-au-Prince, Haiti

3. Hopital Immaculeé Conception des Cayes, Les Cayes, Haiti

4. Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee

Abstract

ABSTRACT With global efforts to scale up the prevention of mother-to-child transmission services and pediatric antiretroviral therapy, there is an urgent need to introduce a simple, low-cost infant human immunodeficiency virus test in the field. We postulated that the p24 antigen capture enzyme-linked immunosorbent assay could be simplified by eliminating signal amplification without compromising diagnostic accuracy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01314-07

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