Treatment of Vancomycin-Resistant Enterococcal Infections in the Immunocompromised Host: Quinupristin-Dalfopristin in Combination with Minocycline-Reference-Cited by-同舟云学术

Treatment of Vancomycin-Resistant Enterococcal Infections in the Immunocompromised Host: Quinupristin-Dalfopristin in Combination with Minocycline

Published:2001-11 Issue:11 Volume:45 Page:3202-3204
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Raad Issam¹,Hachem Ray¹,Hanna Hend¹,Girgawy Essam¹,Rolston Kenneth¹,Whimbey Estella¹,Husni Rola¹,Bodey Gerald¹

Affiliation:

1. Section of Infectious Diseases, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4095

Abstract

ABSTRACT Between February 1994 and November 1998, 56 oncology patients infected with vancomycin-resistant enterococci (VRE) were treated with quinopristin-dalfopristin (Q-D) plus minocycline (MIN). Infections included bacteremia, urinary tract infection, pneumonia, and wound infection. The response rate was 68%, and the most frequent adverse event was arthralgia or myalgia (36%). Q-D–MIN is effective for VRE infection in cancer patients but is associated with a substantial frequency of arthralgia or myalgia.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.11.3202-3204.2001

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