Affiliation:
1. Rowett Research Institute, Bucksburn, Aberdeen, United Kingdom AB21 9SB
Abstract
ABSTRACT
A novel tetracycline resistance gene, designated
tet
(32), which confers a high level of tetracycline resistance, was identified in the
Clostridium-
related human colonic anaerobe K10, which also carries
tet
(W).
tet
(32) was transmissible in vitro to the rumen anaerobe
Butyrivibrio fibrisolvens
2221
R
. The predicted gene product of
tet
(32) has 76% amino acid identity with Tet(O). PCR amplification indicated that
tet
(32) is widely distributed in the ovine rumen and in porcine feces.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
67 articles.
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