Novel Tetracycline Resistance Gene, tet (32), in the Clostridium -Related Human Colonic Anaerobe K10 and Its Transmission In Vitro to the Rumen Anaerobe Butyrivibrio fibrisolvens

Author:

Melville Claire M.1,Scott Karen P.1,Mercer Derry K.1,Flint Harry J.1

Affiliation:

1. Rowett Research Institute, Bucksburn, Aberdeen, United Kingdom AB21 9SB

Abstract

ABSTRACT A novel tetracycline resistance gene, designated tet (32), which confers a high level of tetracycline resistance, was identified in the Clostridium- related human colonic anaerobe K10, which also carries tet (W). tet (32) was transmissible in vitro to the rumen anaerobe Butyrivibrio fibrisolvens 2221 R . The predicted gene product of tet (32) has 76% amino acid identity with Tet(O). PCR amplification indicated that tet (32) is widely distributed in the ovine rumen and in porcine feces.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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5. The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species combinations.;Collins M. D.;Int. J. Syst. Bacteriol.,1994

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