Susceptibilities of Oral Bacteria and Yeast to Mammalian Cathelicidins-Reference-Cited by-同舟云学术

Susceptibilities of Oral Bacteria and Yeast to Mammalian Cathelicidins

Published:2001-11 Issue:11 Volume:45 Page:3216-3219
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Guthmiller Janet M.¹²,Vargas Kaaren G.³²,Srikantha Rupasree²,Schomberg Lori L.²,Weistroffer Paula L.²,McCray Paul B.⁴,Tack Brian F.⁵

Affiliation:

1. Departments of Periodontics1 and

2. Dows Institute for Dental Research,2

3. Pediatric Dentistry3 and

4. College of Dentistry, and Departments of Pediatrics4 and

5. Microbiology,5 College of Medicine, University of Iowa, Iowa City, Iowa

Abstract

ABSTRACT The effects of cathelicidins against oral bacteria and clinically important oral yeasts are not known. We tested the susceptibilities of Actinobacillus actinomycetemcomitans , Fusobacterium nucleatum , Porphyromonas gingivalis , Streptococcus sanguis , Candida krusei , Candida tropicalis and Candida albicans to the following cathelicidins: FALL39, SMAP29, and CAP18. SMAP29 and CAP18 were antimicrobial, whereas FALL39 did not exhibit antimicrobial activity. Future studies are needed to determine the potential use of these antimicrobial peptides in prevention and treatment of oral infections.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.11.3216-3219.2001

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