Hyperbaric Oxygen as an Adjunct in Zygomycosis: Randomized Controlled Trial in a Murine Model-Reference-Cited by-同舟云学术

Hyperbaric Oxygen as an Adjunct in Zygomycosis: Randomized Controlled Trial in a Murine Model

Published:2001-12 Issue:12 Volume:45 Page:3601-3602
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Barratt Diana Marie¹²,Van Meter Keith¹²,Asmar Philip³,Nolan Terry²,Trahan Chris³,Garcia-Covarrubias Lisardo⁴,Metzinger Stephen E.³

Affiliation:

1. Section of Emergency Medicine and Hyperbaric Medicine, Department of Medicine,1 and

2. Baromedical Research Institute, New Orleans, Louisiana 701142; and

3. Department of Otolaryngology, Head and Neck Surgery,3 Louisiana State University, New Orleans, Louisiana 70112;

4. Department of Surgery, University of South Carolina, Columbia, South Carolina 292034

Abstract

ABSTRACT Zygomycosis was induced by injecting CD-1 mice with 5 mg of intraperitoneal deferoxamine and then 10 6 CFU of intravenous and intrasinus Rhizopus arrhizus . The addition of hyperbaric oxygen (2.0 atm absolute twice daily) to amphotericin B did not improve survival over that achieved with amphotericin B and placebo air treatments.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.12.3601-3602.2001

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5. Deferoxamine therapy and mucormycosis in dialysis patients: report of an international registry.;Boelaert J. R.;Am. J. Kidney Dis.,1991

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