In Vitro and In Vivo Activities of Sitafloxacin against Chlamydia spp-Reference-Cited by-同舟云学术

In Vitro and In Vivo Activities of Sitafloxacin against Chlamydia spp

Published:2001-11 Issue:11 Volume:45 Page:3270-3272
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Miyashita Naoyuki¹,Niki Yoshihito¹,Matsushima Toshiharu¹

Affiliation:

1. Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, Japan

Abstract

ABSTRACT The in vitro and in vivo antichlamydial activity of sitafloxacin was investigated. The MICs and minimal chlamydiacidal concentrations of sitafloxacin for various species of chlamydia ranged from 0.031 to 0.125 μg/ml. Sitafloxacin had an excellent therapeutic effect on experimental Chlamydia psittaci pneumonia and was more potent than tosufloxacin, ofloxacin, and ciproflxacin, although slightly less potent than sparfloxacin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.11.3270-3272.2001

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