A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2-Reference-Cited by-同舟云学术

A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2

Published:2000-11 Issue:21 Volume:182 Page:6254-6258
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Miller Jennifer C.¹,Bono James L.²,Babb Kelly¹,El-Hage Nazira¹,Casjens Sherwood³,Stevenson Brian¹

Affiliation:

1. Department of Microbiology and Immunology, University of Kentucky College of Medicine, Lexington, Kentucky 40536-02981;

2. Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 598402; and

3. Division of Molecular Biology and Genetics, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 841323

Abstract

ABSTRACT Although sequence analysis of Borrelia burgdorferi isolate B31 was recently declared “complete,” we found that cultures of this strain can contain a novel 9-kb circular plasmid, cp9-2. The newly described plasmid contains both sequence similarities with and differences from the previously identified B31 plasmid cp9-1 (formerly cp9). cp9-1 and cp9-2 each encode a unique allele of EppA, a putative membrane protein synthesized by B. burgdorferi during mammalian infection.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.182.21.6254-6258.2000

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