Affiliation:
1. Department of Bacterial Immunology, Walter Reed Army Institute of Research, Washington, D.C. 20307-5100.
Abstract
A DNA probe was used to detect Salmonella typhi from blood samples from 14 of 33 patients with culture-confirmed typhoid fever, using the equivalent of 2.5 ml of blood. In contrast, S. typhi was detected in 17 of the same 33 patients by culture of 8 ml of blood. The probe hybridized to blood samples of 4 of 47 patients from whom S. typhi was not isolated.
Publisher
American Society for Microbiology
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