An Epigenetic Journey: Epstein-Barr Virus Transcribes Chromatinized and Subsequently Unchromatinized Templates during Its Lytic Cycle-Reference-Cited by-同舟云学术

An Epigenetic Journey: Epstein-Barr Virus Transcribes Chromatinized and Subsequently Unchromatinized Templates during Its Lytic Cycle

Published:2019-04-15 Issue:8 Volume:93 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chakravorty Adityarup¹,Sugden Bill²,Johannsen Eric C.¹²

Affiliation:

1. McArdle Laboratory for Cancer Research, University of Wisconsin—Madison, Madison, Wisconsin, USA

2. Department of Medicine, School of Medicine and Public Health, University of Wisconsin—Madison, Madison, Wisconsin, USA

Abstract

The Epstein-Barr virus (EBV) lytic phase, like those of all herpesviruses, proceeds via an orderly cascade that integrates DNA replication and gene expression. EBV early genes are expressed independently of viral DNA amplification, and several early gene products facilitate DNA amplification.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02247-18

Reference93 articles.

1. The herpes simplex virus VP16-induced complex: the makings of a regulatory switch