Herpes Simplex Virus 1 UL34 Mutants That Affect Membrane Budding Regulation and Nuclear Lamina Disruption-Reference-Cited by-同舟云学术

Herpes Simplex Virus 1 UL34 Mutants That Affect Membrane Budding Regulation and Nuclear Lamina Disruption

Published:2021-08-10 Issue:17 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Vu Amber¹,White Shaowen²,Cassmann Tiffany²,Roller Richard J.²^ORCID

Affiliation:

1. Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA

2. Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA

Abstract

Herpesvirus nuclear egress is a complex, regulated process coordinated by two virus proteins that are conserved among the herpesviruses that form a heterodimeric nuclear egress complex (NEC). The NEC drives budding of capsids at the inner nuclear membrane and recruits other viral and host cell proteins for disruption of the nuclear lamina, membrane scission, and fusion.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

National Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00873-21

Reference38 articles.

1. Herpesvirus Nuclear Egress

2. Structural basis of membrane budding by the nuclear egress complex of herpesviruses