Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice-Reference-Cited by-同舟云学术

Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice

Published:2021-08-10 Issue:17 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Silvas Jesus A.¹^ORCID,Vasquez Desarey Morales¹,Park Jun-Gyu¹,Chiem Kevin¹,Allué-Guardia Anna¹,Garcia-Vilanova Andreu¹,Platt Roy Neal¹,Miorin Lisa²³,Kehrer Thomas²³⁴,Cupic Anastasija²³,Gonzalez-Reiche Ana S.⁵,Bakel Harm van⁵,García-Sastre Adolfo²³⁶⁷^ORCID,Anderson Tim¹,Torrelles Jordi B.¹,Ye Chengjin¹,Martinez-Sobrido Luis¹^ORCID

Affiliation:

1. Texas Biomedical Research Institute, San Antonio, Texas, USA

2. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA

3. Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA

4. Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA

5. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA

6. Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA

7. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA

Abstract

Despite great efforts put forward worldwide to combat the current coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a human health and socioeconomic threat. Insights into the pathogenesis of SARS-CoV-2 and the contribution of viral proteins to disease outcome remain elusive.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00402-21

Reference43 articles.

1. Origin and evolution of pathogenic coronaviruses

2. SARS and MERS: recent insights into emerging coronaviruses

3. Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

4. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation

5. Molecular epidemiology, evolution and phylogeny of SARS coronavirus

Cited by 92 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Upping the ante: enhanced expression of interferon-antagonizing ORF6 and ORF9b proteins by SARS-CoV-2 variants of concern;Current Opinion in Microbiology;2024-06

2. Interferon signaling in the nasal epithelium distinguishes among lethal and common cold coronaviruses and mediates viral clearance;Proceedings of the National Academy of Sciences;2024-05-17

3. Virological characteristics correlating with SARS-CoV-2 spike protein fusogenicity;Frontiers in Virology;2024-03-14

4. SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle;Nature Communications;2024-03-06

5. Feline infectious peritonitis virus ORF7a is a virulence factor involved in inflammatory pathology in cats;Antiviral Research;2024-02