Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain-Reference-Cited by-同舟云学术

Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain

Published:2021-10-13 Issue:21 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Tripathi Aarti¹,Singh Rawat Bhupendra²,Addya Sankar³,Surjit Milan¹,Tailor Prafullakumar²,Vrati Sudhanshu⁴,Banerjee Arup¹⁴^ORCID

Affiliation:

1. Translational Health Science and Technology Institute (THSTI), Faridabad, India

2. National Institute of Immunology (NII), New Delhi, India

3. Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

4. Regional Center for Biotechnology (RCB), Faridabad, India

Abstract

Microglial cells, the resident macrophages in the brain, play a vital role in Japanese encephalitis virus (JEV) pathogenesis. The deregulated activity of microglia can be lethal for the brain.

Funder

DST | Science and Engineering Research Board

Indian Council of Medical Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00406-21

Reference41 articles.

1. Estimated global incidence of Japanese encephalitis:

2. Recent advances in understanding Japanese encephalitis