Affiliation:
1. Institut für Mikrobiologie und Molekularbiologie, Universität Hohenheim, 7 Stuttgart 70, Germany
Abstract
Haploid strains of
Saccharomyces cerevisiae
with mutations in two different
rib
genes were constructed. These strains were studied by tetrad analysis and by quantitative determination of accumulation products. The genes
rib
1
,
rib
7
, and
rib
2
are not linked to each other.
rib
1
-
rib
7
strains and
rib
1
-
rib
2
strains exhibit the phenotypic properties of
rib
1
strains.
rib
7
-
rib
2
strains show the phenotypic properties of
rib
7
strains. The results support the conclusion that the genes
rib
1
and
rib
7
code for the first and second enzyme of the riboflavine pathway, respectively.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference15 articles.
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2. Accumulation of 2,5- diamino-6-hydroxy-4-ribitylaminopyrimidine in a riboflavin-deficient mutant of Saccharomyes cerevisiae;Bacher A.;Angew. Chem.,1968
3. The structure of the purine prescursor in riboflavin biosynthesis;Bacher A.;Angew. Chem.,1969
4. Biosynthesis of riboflavin;Bacher A.;Formation of,1970
5. Biosynthesis of riboflavin. Formation of 6-hydroxy-2, 4, 5-triaminopyrimidine in rib 7 mutants of Saccharomyces cerevisiae;Bacher A.;J. Biol. Chem.,1971
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