Affiliation:
1. Department of the Army, Fort Detrick, Frederick, Maryland
Abstract
A method was developed to evaluate and measure the sporicidal activity of peracetic acid (PAA) and β-propiolactone (BPL) at subzero temperatures as low as -40 C.
Bacillus subtilis
var.
niger
spores were used as the test organism. Both PAA and BPL were sporicidal at low temperatures, with PAA the more active. The temperature coefficients of the two chemicals are generally low over a range of 20 to -20 C, but increase significantly at temperatures below this. Results showed an initial lag in the PAA death rates that was directly dependent on the temperature. BPL did not show this lag time.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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