Affiliation:
1. The Upjohn Company, Kalamazoo, Michigan
Abstract
The dose response curves of various turbidimetric microbiological assays, including vitamin B
12
, Ca pantothenate, and pyridoxine (vitamin B
6
), were linear with logarithmic transformation of the responses by use of the equation derived,
ln
[
T
(
x
) -
T
(∞)] =
ln A - Bx
. A Fortran computer program which used the slope ratio potency calculation was written. The assay potencies calculated by the computer program showed excellent agreement with those obtained by the manual calculation.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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