Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading <i>Firmicutes</i> from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity-Reference-Cited by-同舟云学术

Hungatella hathewayi, an Efficient Glycosaminoglycan-Degrading Firmicutes from Human Gut and Its Chondroitin ABC Exolyase with High Activity and Broad Substrate Specificity

Published:2022-11-22 Issue:22 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Rawat Parkash Singh¹,Li Yan²,Zhang Weixin¹,Meng Xiangfeng¹^ORCID,Liu Weifeng¹^ORCID

Affiliation:

1. State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, People’s Republic of China

2. Department of Pathogen Biology, School of Basic Medical Science, Shandong University, Jinan, People’s Republic of China

Abstract

An increased understanding of GAG metabolism by intestinal bacteria is critical in identifying the driving factors for the composition, modulation, and homeostasis of the human gut microbiota. In addition, GAG-depolymerizing polysaccharide lyases are highly desired enzymes for the production of GAG oligosaccharides and as therapeutics.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Young Scholars Program of Shandong University

Major Basic Research of Shandong Provincial Natural Science Foundation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.01546-22

Reference68 articles.