Structure and Infectivity of Picornaviral RNA Encapsidated by Cowpea Chlorotic Mottle Virus Protein-Reference-Cited by-同舟云学术

Structure and Infectivity of Picornaviral RNA Encapsidated by Cowpea Chlorotic Mottle Virus Protein

Published:1973-12 Issue:6 Volume:12 Page:1209-1215
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Black Douglas R.¹²,Connell Carolyn J.¹²,Merigan Thomas C.¹²

Affiliation:

1. Life Sciences Division, Stanford Research Institute, Menlo Park, California 94025

2. Division of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305

Abstract

Poliovirus and Mengo virus RNA were shown to associate efficiently with cowpea chlorotic mottle virus protein to form pseudovirions. The sedimentation coefficient for the pseudovirions was similar to that of poliovirus, and electron microscope observations showed the Mengo pseudovirions to be similar in size to Mengo virus. Such pseudovirions were infectious and were more resistant to ribonuclease than viral RNA; however, under our assay conditions, their infectivity was about equal to that of viral RNA.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.12.6.1209-1215.1973

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