Echinocandin Resistance in Two Candida haemulonii Isolates from Pediatric Patients

Author:

Dominguez Muro Marisol12,Motta Fábio de Araújo2,Burger Marion23,Melo Analy Salles de Azevedo4,Dalla-Costa Líbera Maria12

Affiliation:

1. Hospital de Clínicas, Universidade Federal do Paraná Curitiba, Paraná, Brazil

2. Hospital, Faculdades, and Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba, Paraná, Brazil

3. Secretaria Municipal da Saúde de Curitiba, Paraná, Brazil

4. Laboratório Especial de Micologia, Universidade Federal de São Paulo, São Paulo, Brazil

Abstract

ABSTRACT We report 3 cases of patients with Candida haemulonii isolates that were obtained from hemocultures. In 2 of the 3 cases, isolates exhibited resistance to echinocandins and fluconazole. This is the first report of an echinocandin-resistant species of this fungus in pediatric patients.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference21 articles.

1. Clinical and Laboratory Standards Institute. 2008. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard M27-A3. Clinical and Laboratory Standards Institute, Wayne, PA.

2. Clinical and Laboratory Standards Institute. 2008. Reference method for broth dilution antifungal susceptibility testing of yeasts. Information supplement M27-S3. Clinical and Laboratory Standards Institute, Wayne, PA.

3. Outbreak of Fungemia among Neonates Caused by Candida haemulonii Resistant to Amphotericin B, Itraconazole, and Fluconazole

4. Candida haemulonii and closely related species at 5 university hospitals in Korea: identification, antifungal susceptibility, and clinical features;Kim MN;Clin. Infect. Dis.,2009

5. Identification of Medically Important Yeast Species by Sequence Analysis of the Internal Transcribed Spacer Regions

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