Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii-Reference-Cited by-同舟云学术

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

Published:2020-06-30 Issue:3 Volume:11 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Rastogi Suchita¹^ORCID,Xue Yuan²,Quake Stephen R.²³⁴,Boothroyd John C.²

Affiliation:

1. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA

2. Department of Bioengineering, Stanford University, Stanford, California, USA

3. Department of Applied Physics, Stanford University, Stanford, California, USA

4. Chan Zuckerberg Biohub, San Francisco, California, USA

Abstract

This work performs transcriptomic analysis of U-I cells, captures the earliest stage of a host cell’s interaction with Toxoplasma gondii , and dissects the effects of individual classes of parasite effectors on host cell biology.

Funder

Stanford Interdisciplinary Graduate Bio-X Fellowship

Chan Zuckerberg Biohub

National Institutes of Health S10 Shared Instrument Grant

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00182-20

Reference71 articles.

1. Beatty CP, Dubey JP. 1988. Toxoplasmosis of animals and man. CRC Press, Boca Raton, FL.

2. Lytic Cycle of Toxoplasma gondii: 15 Years Later

3. Translocation of effector proteins into host cells by Toxoplasma gondii

4. A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins

5. The Toxoplasma Pseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases

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