CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma-Reference-Cited by-同舟云学术

CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma

Published:2023-06-27 Issue:3 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Kurhade Chaitanya¹,Kang Soowon¹,Biering Scott B.²,Hwang Seungmin³^ORCID,Randall Glenn¹^ORCID

Affiliation:

1. Department of Microbiology, The University of Chicago, Chicago, Illinois, USA

2. Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, USA

3. Department of Pathology, The University of Chicago, Chicago, Illinois, USA

Abstract

Replication complexes provide a microenvironment important for (+) RNA virus replication and shield it from host immune response. Previously we have shown that interferon gamma (IFNG) disrupts the RC of MNV via evolutionarily conserved autophagy proteins and IFN-inducible GTPases.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00172-23

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