Evolution of the Quorum Sensing Regulon in Cooperating Populations of Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Evolution of the Quorum Sensing Regulon in Cooperating Populations of Pseudomonas aeruginosa

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Smalley Nicole E.¹,Schaefer Amy L.²^ORCID,Asfahl Kyle L.¹^ORCID,Perez Crystal²,Greenberg E. Peter²^ORCID,Dandekar Ajai A.¹²^ORCID

Affiliation:

1. Department of Medicine, University of Washington, Seattle, Washington, USA

2. Department of Microbiology, University of Washington, Seattle, Washington, USA

Abstract

Pseudomonas aeruginosa uses quorum sensing (QS) to activate expression of dozens of genes (the QS regulon). Because there is strain-to-strain variation in the size and content of the QS regulon, we asked how the regulon might evolve during long-term P. aeruginosa growth when cells require some but not all the functions activated by QS.

Funder

Burroughs Wellcome Fund

Cystic Fibrosis Foundation

Doris Duke Charitable Foundation

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00161-22

Reference49 articles.