Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes-Reference-Cited by-同舟云学术

Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Hilterbrand Adam T.¹^ORCID,Daly Raecliffe E.¹²,Heldwein Ekaterina E.¹²^ORCID

Affiliation:

1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

2. Graduate Program in Cellular, Molecular, and Developmental Biology, Tufts University School of Medicine, Boston, Massachusetts, USA

Abstract

Herpes simplex viruses (HSV-1 and HSV-2) contain up to 16 different proteins in their envelopes. Four of these, glycoproteins gB, gD, gH, and gL, are termed essential with regard to entry, whereas the rest are typically referred to as nonessential based on the entry phenotypes of the respective single genetic deletions.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Howard Hughes Medical Institute

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00143-21

Reference110 articles.

1. Update on Herpes Virus Infections of the Nervous System

2. Seroprevalence of Herpes Simplex Virus Types 1 and 2--United States, 1999-2010