First Characterization of CTX-M-15-Producing Escherichia coli Strains Belonging to Sequence Type (ST) 410, ST224, and ST1284 from Commercial Swine in South America

Author:

Silva Ketrin C.1,Moreno Marina1,Cabrera Carlos1,Spira Beny2,Cerdeira Louise23,Lincopan Nilton23ORCID,Moreno Andrea M.1ORCID

Affiliation:

1. Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil

2. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

3. Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil

Abstract

ABSTRACT We report for the first time the isolation of CTX-M-15-producing Escherichia coli strains belonging to sequence type (ST) 410, ST224, and ST1284 in commercial swine in Brazil. The bla CTX-M-15 gene was located on F-::A9::B1 and C1::A9::B1 IncF-type plasmids, surrounded by a new genetic context comprising the IS 26 insertion sequence truncated with the IS Ecp1 element upstream of bla CTX-M-15 . These results reveal that commercial swine have become a new reservoir of CTX-M-15-producing bacteria in South America.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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