Antibiotic Exposure Leads to Reduced Phage Susceptibility in Vancomycin Intermediate Staphylococcus aureus (VISA)

Author:

McCallin Shawna12ORCID,Menzi Carmen1,Lassen Swenja2,Daraspe Jean3,Oechslin Frank1,Moreillon Philippe1

Affiliation:

1. Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland

2. Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland

3. Electron Microscopy Facility, University of Lausanne, Lausanne, Switzerland

Abstract

In the time of antimicrobial resistance, phage therapy is frequently suggested as a possible solution for such difficult-to-treat infections. Vancomycin-intermediate Staphylococcus aureus (VISA) remains a relatively rare yet increasing occurrence in the clinic for which phage therapy may be an option.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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