A Fusidic Acid-Resistant Epidemic Strain of Staphylococcus aureus Carries the fusB Determinant, whereas fusA Mutations Are Prevalent in Other Resistant Isolates-Reference-Cited by-同舟云学术

A Fusidic Acid-Resistant Epidemic Strain of Staphylococcus aureus Carries the fusB Determinant, whereas fusA Mutations Are Prevalent in Other Resistant Isolates

Published:2004-09 Issue:9 Volume:48 Page:3594-3597
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

O'Neill Alexander J.¹,Larsen Anders R.²,Henriksen Anne S.³,Chopra Ian¹

Affiliation:

1. Antimicrobial Research Centre and School of Biochemistry and Microbiology, University of Leeds, Leeds, United Kingdom

2. Department of Research & Development, Statens Serum Institut, Copenhagen

3. LEO Pharma, Ballerup, Denmark

Abstract

ABSTRACT Fusidic acid-resistant epidemic Staphylococcus aureus strains causing impetigo bullosa have been reported in Scandinavia. We show that these strains form part of a European epidemic clonotype that carries the fusB determinant. In contrast, resistance to fusidic acid in a collection of nonepidemic strains resulted primarily from mutations in fusA .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.9.3594-3597.2004

Reference16 articles.

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5. Greenwood, D. 2003. Fusidanes, p. 297-299. In R. G. Finch (ed.), Antibiotic & chemotherapy, 8th ed. Churchill Livingstone, London, United Kingdom.

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