Detection of antibody to cytomegalovirus-induced early antigens and comparison with four serologic assays and presence of viruria in blood donors

Author:

Lentz E B1,Dock N L1,McMahon C A1,Fiesthumel S R1,Arnold C B1,Lamberson H V1

Affiliation:

1. Research and Development Laboratory, American Red Cross Blood Services, Syracuse, New York 13202.

Abstract

Five hundred blood donors were evaluated for cytomegalovirus (CMV) viruria, antibody to CMV early antigens (EA-ab), CMV seropositivity by two screening assays, and CMV-specific immunoglobulin M by two methods. Three donors were viruric, EA-ab positive, and seropositive; two viruric donors were immunoglobulin M positive.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference20 articles.

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2. The significance of non-A, non-B hepatitis, cytomegalovirus and the acquired immunodeficiency syndrome in transfusion practice;Bayer W.;Clin. Haematol.,1984

3. Relation of titers of antibodies of CMV in blood donors to the transmission of cytomegalovirus infection;Beneke J.;J. Infect. Dis.,1984

4. Benyesh-Melnick M. 1969.- Cytomegaloviruses p. 701-732. In E. Lennette and N. Schmidt (ed.) Diagnostic procedures for viral and rickettsial infection. American Public Health Association Washington D.C.

5. Seroconversion to virus-specific pre-early nuclear antigens in infants with primary cytomegalovirus infection;Chiba S.;Infect. Immun.,1980

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