Genetic Basis of Antibiotic Resistance in Clinical Isolates of Streptococcus gallolyticus ( Streptococcus bovis )

Author:

Leclercq Roland1,Huet Corinne1,Picherot Mélanie2,Trieu-Cuot Patrick2,Poyart Claire2

Affiliation:

1. Service de Microbiologie, CHU Côte de Nacre, Caen

2. Laboratoire Mixte Pasteur Necker de Recherche sur les Streptocoques, Faculté de Médecine Necker, Paris, France

Abstract

ABSTRACT Among 128 Streptococcus gallolyticus ( Streptococcus bovis ) isolates, 77.7% were resistant to tetracyclines and contained tet (M) and/or tet (L) and/or tet (O). A total of 59.4% had macrolide resistance and contained erm (B) and, rarely, mef (A). Among the one-third of isolates highly resistant to kanamycin and streptomycin, most harbored aphA3 and aad-6 genes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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