Report of Two Cases of Aseptic Meningitis with Persistence of Pneumococcal Cell Wall Components in Cerebrospinal Fluid after Pneumococcal Meningitis

Author:

Angoulvant François1,Lachenaud Julie1,Mariani-Kurkdjian Patricia2,Aubertin Guillaume1,Houdouin Véronique1,Lorrot Mathie1,de Los Angeles Laure1,Bingen Edouard2,Bourrillon Antoine1,Faye Albert1

Affiliation:

1. Service de Pédiatrie Générale de l'Hôpital Robert Debré, Paris, France

2. Laboratoire de Microbiologie de l'Hôpital Robert Debré, Paris, France

Abstract

ABSTRACT We describe two cases of aseptic meningitis occurring some time after pneumococcal meningitis. Both cases may have resulted from an inflammatory response to persistent pneumococcal cell membrane components, as the cerebrospinal fluid samples were positive by the Binax NOW Streptococcus pneumoniae antigen test. Potential mechanisms and diagnostic impact are discussed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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