CRUISE, a Tool for the Detection of Iterons in Circular Rep-Encoding Single-Stranded DNA Viruses-Reference-Cited by-同舟云学术

CRUISE, a Tool for the Detection of Iterons in Circular Rep-Encoding Single-Stranded DNA Viruses

Published:2023-01-24 Issue:1 Volume:12 Page:
ISSN:2576-098X
Container-title:Microbiology Resource Announcements
language:en
Short-container-title:Microbiol Resour Announc

Author:

Jones Adam¹²,Kasun George W.¹³,Stover Joel¹,Stedman Kenneth M.¹^ORCID,de la Higuera Ignacio¹^ORCID

Affiliation:

1. Department of Biology, Center for Life in Extreme Environments, Portland State University, Portland, Oregon, USA

2. Westview High School, Portland, Oregon, USA

3. AbSci, Vancouver, Washington, USA

Abstract

Iterons are short, repeated DNA sequences that are important for the replication of circular single-stranded DNA viruses. No tools that can reliably predict iterons are currently available. The CRUcivirus Iteron SEarch (CRUISE) tool is a computational tool that identifies iteron candidates near stem-loop structures in viral genomes.

Funder

Apprenticeships in Science and Engineering Program

National Science Foundation

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/mra.01123-22

Reference12 articles.

1. DNA forms of the geminivirus African cassava mosaic virus consistent with a rolling circle mechanism of replication

2. Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria

3. DNA-binding specificity determinants of replication proteins encoded by eukaryotic ssDNA viruses are adjacent to widely separated RCR conserved motifs

4. Rep and Rep′ Protein of Porcine circovirus Type 1 Bind to the Origin of Replication in Vitro

5. Interaction between a geminivirus replication protein and origin DNA is essential for viral replication.