Brucella abortus Depends on l -Serine Biosynthesis for Intracellular Proliferation-Reference-Cited by-同舟云学术

Brucella abortus Depends on l -Serine Biosynthesis for Intracellular Proliferation

Published:2020-01-22 Issue:2 Volume:88 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Révora Virginia¹,Marchesini María Inés¹,Comerci Diego J.¹²

Affiliation:

1. Instituto de Investigaciones Biotecnológicas Dr. Rodolfo A. Ugalde, IIB-UNSAM-CONICET, Universidad Nacional de San Martín, San Martín, Buenos Aires, Argentina

2. Comisión Nacional de Energía Atómica, Grupo Pecuario, Centro Atómico Ezeiza, Buenos Aires, Argentina

Abstract

l -Serine is a nonessential amino acid and a key intermediate in several relevant metabolic pathways. In bacteria, the major source of l -serine is the phosphorylated pathway, which comprises three enzymes: d -3-phosphoglycerate dehydrogenase (PGDH; SerA), phosphoserine amino transferase (PSAT; SerC), and l -phosphoserine phosphatase (PSP; SerB).

Funder

MINCyT | Agencia Nacional de Promoción Científica y Tecnológica

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00840-19

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