Conjugative Plasmid Conferring Resistance to Olaquindox

Author:

Sørensen Anders Hay1,Hansen Lars Hestbjerg1,Johannesen Elsebetta1,Sørensen Søren J.1

Affiliation:

1. Department of General Microbiology, University of Copenhagen, 1307 Copenhagen K, Denmark

Abstract

ABSTRACT A conjugative plasmid, pOLA52, conferring resistance to the antibiotic growth promoter olaquindox has been isolated from Escherichia coli from swine manure. It also confers resistance to ampicillin and chloramphenicol and has a high frequency of transfer between strains of E. coli . Plasmid-borne olaquindox resistance has not been demonstrated before.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

1. Aarestrup, F. M., Y. Agersø, P. Ahrens, J. C. Ø. Jørgensen, M. Madsen, and L. B. Jensen. 2000. Antimicrobial susceptibility and presence of resistance genes in staphylococci from poultry. Vet. Microbiol.74:353-364.

2. Corpet, D. E. 1984. The effect of bambermycin, carbadox, chlortetracycline and olaquindox on antibiotic resistance in intestinal coliforms: a new model. Ann. Microbiol. (Paris)135A:329-339.

3. DANMAP. 1999. DANMAP 98—consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals food and humans in Denmark. Statens Serum Institut Danish Veterinary and Food Administration Danish Medicines Agency Danish Veterinary Laboratory Copenhagen Denmark.

4. New Selective Media for Enumeration and Recovery of Fluorescent Pseudomonads from Various Habitats

5. Hedges, A. J., and A. H. Linton. 1988. Olaquindox resistance in the coliform flora of pigs and their environment: an ecological study. J. Appl. Bacteriol.64:429-443.

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