Insight into the Antibacterial Action of Iodinated Imine, an Analogue of Rafoxanide: a Comprehensive Study of Its Antistaphylococcal Activity

Author:

Krátký Martin1,Konečná Klára2ORCID,Janďourek Ondřej2,Diepoltová Adéla2,Vávrová Pavlína2,Voxová Barbora2,Vejsová Marcela2,Bárta Pavel3,Bősze Szilvia4

Affiliation:

1. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Organic and Bioorganic Chemistry, Hradec Králové, Czech Republic

2. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Biological and Medical Sciences, Hradec Králové, Czech Republic

3. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Biophysics and Physical Chemistry, Hradec Králové, Czech Republic

4. ELKH-ELTE Research Group of Peptide Chemistry, Budapest, Hungary

Abstract

Antibiotic resistance is among the largest threats to global health, with a potentially serious socioeconomic impact. One of the strategies to deal with the predicted catastrophic future scenarios associated with the rapid emergence of resistant infectious agents lies in the discovery and research of new anti-infectives.

Funder

Grantová Agentura České Republiky

Univerzita Karlova v Praze

EC | European Regional Development Fund

Next Generation EU

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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